Dr. Pichardo graduated in physics in 1998 at the University of State of Mexico (UAEM), and the master degree in physics in 1996 at the Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV, Mex). He got his PhD at 2000 a The Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV, Mérida, Mex). In 2002 he joined the Optical Research Center (CIO).
Research Interests:
Dr. Pichardo has been working on phototermal techniques for thermal and thermo-mechanical characterization of diverse material (semiconductors, polymer, metals and tissue). He also has worked on the use of optical spectroscopy like Raman for breast cancer detection in biological fluids from humans also on the analysis of breast cancer on animal models. Actually he is the leader of the lab of biomedical spectroscopy and nanomaterials at CIO. He is working on the synthesis of organic and inorganic nanomaterials for different biomedical applications: a) study the interaction of nanoparticles with cell culture, b) use of fluorescent nanoparticles for markers detection, c) functionalization of nanoparticles (using specific antibodies) for disease detection and d) In the design of surface enhance Raman scattering substrates for single molecular detection.
Recent publications:
2019
- J.L.Pichardo-Molina, P.E.Cardoso-Avila, L.L.Flores-Villavicencio, N.M.Gomez-Ortiz, M.A.Rodriguez-Rivera. FLUORESCENT CARBON NANOPARTICLES SYNTHESIZED FROM BOVINE SERUM ALBUMIN NANOPARTICLES. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, Volume 142, 1 January 2020, Pages 724-731, https://doi.org/10.1016/j.ijbiomac.2019.10.013
2018
2017
- P. E. Cardoso Avila, A. Rangel Mendoza, J. L. Pichardo Molina, L. L. Flores Villavicencio, J. P. Castruita Dominguez, M. K. Chilakapati, M. Sabanero Lopez. Biological response of HeLa cells to gold nanoparticles coated with organic molecules. Toxicology in Vitro Volume 42, August 2017, Pages 114-122. https://doi.org/10.1016/j.tiv.2017.04.013
- Fernando D. Cortes Vega, Pablo G. Martinez Torres, Juan Pichardo Molina, Nikte M. Gomez Ortiz, Viktor G. Hadjiev, Juan Zarate Medina and Francisco C. Robles Hernandez. Gold nanoparticle SERS substrates sustainable at extremely high temperatures. J. Mater. Chem. C, 2017,5, 4959-4966. http://dx.doi.org/10.1039/c7tc00527j
- M. M. Martinez-Garcia, P.E. Cardoso-Avila, N. Gomez-Ortiz and J.L. Pichardo-Molina. Low-cost Functionalized Pseudoboehmite/Aluminum Substrates for the Analysis of Nanoparticles by SEM. Volume 23, Issue S1 (Proceedings of Microscopy & Microanalysis 2017) July 2017 , pp. 800-801. http://dx.doi.org/10.1017/s1431927617004664
- Karla M. Salas-Alcántara, Laura Aparicio-Ixta, Ismael Torres-Gómez, Mario Rodríguez, Gabriel Ramos-Ortiz, Rafael Espinosa-Luna, and Juan L. Pichardo-Molina. Modal interferometer based on a single mechanically induced long-period fiber grating and a nanoparticles-coated film section. Optics Letters Vol. 42, Issue 9, pp. 1780-1783 (2017) https://doi.org/10.1364/OL.42.001780
2016
- A. Corral-Aguado, P. Martínez-Torres, N. Gomez-Ortiz, J. Pichardo-Molina, Susana De la Rosa García, S. E. Borjas-García, A. Medina. Synthesis of Mg doped ZnO with hexagonal shape by hydrothermal method. Microsc. Microanal. 22 (Suppl 3), 2016. doi:10.1017/S1431927616010254
- M.M. Martinez-Garcia, P.E. Cardoso-Avila, J.L. Pichardo-Molina, Concave gold nanocubes on Al-6063 alloy as a simple and efficient SERS substrate, Colloids and Surfaces A: Physicochemical and Engineering Aspects Volume 493, 20 March 2016, Pages 66–73
- Laura Aparicio-Ixta1, J. E. Alba-Rosales, Gabriel Ramos-Ortiz, Mario Rodriguez, Juan L. Pichardo-Molina, Gerardo Gutierrez-Juarez, Myrna Sabanero-Lopez, Liss Flores Villavicencio, Rosa Santillan, Víctor M. Tellez-Lopez and Daniel Martinez-Fong, Two-Photon Imaging of a Cellular Line Using Organic Fluorescent Nanoparticles Synthesized by Laser Ablation, Particle & Particle Systems Characterization Volume 33, Issue 2, pages 101–109, February 2016
2015
- Pablo Genaro Martínez-Torres, Monica Monserrat Martínez-García, Pablo Eduardo Cardoso-Ávila and Juan Luis Pichardo-Molina Facile Nanostructured Substrate Preparation Using Gold Nanocuboids for SERS, Nanomaterials and Nanotechnology, 5:12, pp. 1-7, F.I.: 0.857, DOI:10.5772/60500.
- P. E. Cardoso-Avila, J. L. Pichardo-Molina,C. Murali Krishna, R. Castro-Beltran. Photochemical transformation of silver nanoparticles, J Nanopart Research, J Nanopart Res. Vol 17 (2015) 160, DOI 10.1007/s11051-015-2920-x
- L. Rocha-Osornio, J. L. Pichardo-Molina, G. Barbosa-Sabanero, J. M. de la Roca, C. Frausto-Reyes, R. Huerta-Franco, J. A. Martínez-García. Characterization of Breast Cancer Tissue From a Rat Model With and Without Cancer: The Use of Raman Spectroscopy. Spectroscopy Letters: An International Journal for Rapid Communication. Vol. 48:6, pp. 393-402, DOI: 10.1080/00387010.2014.895386
- Sanhita Rath, Aditi Sahu†, Vikram Gota, P. G. Martínez-Torres, J. L. Pichardo-Molina, and C. Murali Krishna. Raman spectroscopy for detection of imatinib in plasma: A proof of concept. Journal of Innovative Optical Health Sciences Vol. 8, No. 5, 1550019. DOI: 10.1142/S1793545815500194
2014
- Yenisey Ponce de León, J. L. Pichardo-Molina, Noé Alcalá Ochoa. Growth Kinetics of Concave Nanocubes Studied by Optical Coherence Tomography. Plasmonics Vol. 9 pp. 907–915 DOI 10.1007/s11468-014-9696-1
2012
- Y. Ponce de león, J.L. Pichardo-Molina, N. Alacalá Ochoa, D. Luna-Moreno, Contrast enhancement of optical coherence tomography images using barnched gold nanoparticles, Journal of Nanomaterials, VOL. 2012, ID 571015, 9 pages, doi: 10.1155/2012/571015 (2012)
- L. Aparicio-Ixta, G. Ramos-Ortiz, J.L. PichardoJ.L. Maldonado, M. Rodríguez, V. M. Tellez-Lopez, D. Martínez-Fong, M.G. Zolotukhin, S. Fomine, M.A. Meneses-Nava, O. Barbosa- García, Two-photon excited fluorescence of silica nanoparticles loaded with a fluorene-based monomer and its cross-conjugated polymer: their application to cell imaging, Nanoscale, vol. 4, pp 7751-7759 (2012)
2010
- A.C. Muñoz-Muñoz, J.L. Pichardo, G. Ramos, O. Barbosa-García, J.L. Maldonado, M.A. Meneses, N.E. Ornelas, A. Escobedo, P.L López-de-Alba, Identification and quantification of furanic compounds in tequila and mezcal using spectroscopy and chemometric methods, Journal of the Brazilian Chemical Society, Vol. 21, No. 6, pp 1077-1087 (2010)
- U. Contreras, O. Barbosa-García, J.L. Pichardo, G. Ramos Ortiz, J.L. Maldonado, M.A. Meneses, N.E. Ornelas, A. Escobedo, P.L López-de-Alba, Screening method for identification of adulterate and fake tequilas by using UV-VIS spectroscopy and chemometrics, Food Reseach International, vol. 42, pp 2356-2362 (2010)
2009
- R. Ivanov, E. Marín, J.L. Pichardo, I. Moreno, C. Araujo, Differential sensor in front photopyroelectric technique: II . Experimental, Journal of physics D: Applied Physics, Vol. 42, 125504-1 a 125504-8 (2009)
- G. Ramos, S. Romero, J.L. Maldonado, M. A. Meneses, O. Barbosa, P. Zapata, M. A. Mendez, H. Höpfl, Synthesis and optical nonlinearities of a 2-Amino- 1,23,- triazolquinone derivative, Mol. Cryst. Liq. Cryst, Vol. 515, pp 109-124 (2009)